Simulation of two‐phase air–liquid flows in a closed bioreactor loop: Numerical modeling, experiments, and verification

Improvements in technology for the production of microbial biomass from natural gas, which have been gaining importance recent years, require development and optimization energy-efficient bioreactor designs. The most advanced methods developing scaling up industrial biotechnological processes rely on detailed hydrodynamic modeling, addition to classical approaches, as main tool analysis large-scale transfer experimental information. This paper presents results a simulation flows circuit using latest mathematical numerical flow tools two-phase bubble based data.